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1.

Distinct baseline immune characteristics associated with responses to conjugated and unconjugated pneumococcal polysaccharide vaccines in older adults.

Ravichandran, Sathyabaarathi; Erra-Diaz, Fernando; Karakaslar, Onur E; Marches, Radu; Kenyon-Pesce, Lisa; Rossi, Robert; Chaussabel, Damien; Nehar-Belaid, Djamel; LaFon, David C; Pascual, Virginia; Palucka, Karolina; Paust, Silke; Nahm, Moon H; Kuchel, George A; Banchereau, Jacques; Ucar, Duygu.

Nat Immunol; 25(2): 316-329, 2024 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-38182669

2.

Mapping systemic lupus erythematosus heterogeneity at the single-cell level.

Nehar-Belaid, Djamel; Hong, Seunghee; Marches, Radu; Chen, Guo; Bolisetty, Mohan; Baisch, Jeanine; Walters, Lynnette; Punaro, Marilynn; Rossi, Robert J; Chung, Cheng-Han; Huynh, Richie P; Singh, Prashant; Flynn, William F; Tabanor-Gayle, Joy-Ann; Kuchipudi, Navya; Mejias, Asuncion; Collet, Magalie A; Lucido, Anna Lisa; Palucka, Karolina; Robson, Paul; Lakshminarayanan, Santhanam; Ramilo, Octavio; Wright, Tracey; Pascual, Virginia; Banchereau, Jacques F.

Nat Immunol; 21(9): 1094-1106, 2020 09.

Artículo en Inglés | MEDLINE | ID: mdl-32747814

3.

Sestrins induce natural killer function in senescent-like CD8⁺ T cells.

Pereira, Branca I; De Maeyer, Roel P H; Covre, Luciana P; Nehar-Belaid, Djamel; Lanna, Alessio; Ward, Sophie; Marches, Radu; Chambers, Emma S; Gomes, Daniel C O; Riddell, Natalie E; Maini, Mala K; Teixeira, Vitor H; Janes, Samuel M; Gilroy, Derek W; Larbi, Anis; Mabbott, Neil A; Ucar, Duygu; Kuchel, George A; Henson, Sian M; Strid, Jessica; Lee, Jun H; Banchereau, Jacques; Akbar, Arne N.

Nat Immunol; 21(6): 684-694, 2020 06.

Artículo en Inglés | MEDLINE | ID: mdl-32231301

4.

Transcriptional activation of Jun and Fos members of the AP-1 complex is a conserved signature of immune aging that contributes to inflammaging.

Karakaslar, Emin Onur; Katiyar, Neerja; Hasham, Muneer; Youn, Ahrim; Sharma, Siddhartha; Chung, Cheng-Han; Marches, Radu; Korstanje, Ron; Banchereau, Jacques; Ucar, Duygu.

Aging Cell; 22(4): e13792, 2023 04.

Artículo en Inglés | MEDLINE | ID: mdl-36840360

5.

Concomitant inhibition of PPARÎ³ and mTORC1 induces the differentiation of human monocytes into highly immunogenic dendritic cells.

Erra Diaz, Fernando; Mazzitelli, Ignacio; Bleichmar, Lucía; Melucci, Claudia; Thibodeau, Asa; Dalotto Moreno, Tomás; Marches, Radu; Rabinovich, Gabriel A; Ucar, Duygu; Geffner, Jorge.

Cell Rep; 42(3): 112156, 2023 03 28.

Artículo en Inglés | MEDLINE | ID: mdl-36842088

6.

Distinct baseline immune characteristics associated with responses to conjugated and unconjugated pneumococcal polysaccharide vaccines in older adults.

Ravichandran, Sathyabaarathi; Erra-Diaz, Fernando; Karakaslar, Onur E; Marches, Radu; Kenyon-Pesce, Lisa; Rossi, Robert; Chaussabel, Damien; Pascual, Virginia; Palucka, Karolina; Paust, Silke; Nahm, Moon H; Kuchel, George A; Banchereau, Jacques; Ucar, Duygu.

medRxiv; 2023 Apr 19.

Artículo en Inglés | MEDLINE | ID: mdl-37131707

7.

Young infants display heterogeneous serological responses and extensive but reversible transcriptional changes following initial immunizations.

Nouri, Nima; Cao, Raquel Giacomelli; Bunsow, Eleonora; Nehar-Belaid, Djamel; Marches, Radu; Xu, Zhaohui; Smith, Bennett; Heinonen, Santtu; Mertz, Sara; Leber, Amy; Smits, Gaby; van der Klis, Fiona; Mejías, Asunción; Banchereau, Jacques; Pascual, Virginia; Ramilo, Octavio.

Nat Commun; 14(1): 7976, 2023 Dec 02.

Artículo en Inglés | MEDLINE | ID: mdl-38042900

8.

An unconventional mechanism of IL-1ß secretion that requires Type I IFN in lupus monocytes.

Caielli, Simone; Balasubramanian, Preetha; Rodriguez-Alcazar, Juan; Balaji, Uthra; Wan, Zurong; Baisch, Jeanine; Smitherman, Cynthia; Walters, Lynnette; Sparagana, Paola; Nehar-Belaid, Djamel; Marches, Radu; Nassi, Lorien; Stewart, Katie; Fuller, Julie; Banchereau, Jacques F; Gu, Jinghua; Wright, Tracey; Pascual, Virginia.

bioRxiv; 2023 Aug 03.

Artículo en Inglés | MEDLINE | ID: mdl-37577613

9.

The Th1/Tfh-like biased responses elicited by the rASP-1 innate adjuvant are dependent on TRIF and Type I IFN receptor pathways.

George, Parakkal Jovvian; Marches, Radu; Nehar-Belaid, Djamel; Banchereau, Jacques; Lustigman, Sara.

Front Immunol; 13: 961094, 2022.

Artículo en Inglés | MEDLINE | ID: mdl-36119026

10.

The importance of cellular internalization of antibody-targeted carbon nanotubes in the photothermal ablation of breast cancer cells.

Marches, Radu; Mikoryak, Carole; Wang, Ru-Hung; Pantano, Paul; Draper, Rockford K; Vitetta, Ellen S.

Nanotechnology; 22(9): 095101, 2011 Mar 04.

Artículo en Inglés | MEDLINE | ID: mdl-21258147

11.

Thermal ablation of tumor cells with antibody-functionalized single-walled carbon nanotubes.

Chakravarty, Pavitra; Marches, Radu; Zimmerman, Neil S; Swafford, Austin D-E; Bajaj, Pooja; Musselman, Inga H; Pantano, Paul; Draper, Rockford K; Vitetta, Ellen S.

Proc Natl Acad Sci U S A; 105(25): 8697-702, 2008 Jun 24.

Artículo en Inglés | MEDLINE | ID: mdl-18559847

12.

AMULET: a novel read count-based method for effective multiplet detection from single nucleus ATAC-seq data.

Thibodeau, Asa; Eroglu, Alper; McGinnis, Christopher S; Lawlor, Nathan; Nehar-Belaid, Djamel; Kursawe, Romy; Marches, Radu; Conrad, Daniel N; Kuchel, George A; Gartner, Zev J; Banchereau, Jacques; Stitzel, Michael L; Cicek, A Ercument; Ucar, Duygu.

Genome Biol; 22(1): 252, 2021 09 01.

Artículo en Inglés | MEDLINE | ID: mdl-34465366

13.

Sexual-dimorphism in human immune system aging.

Márquez, Eladio J; Chung, Cheng-Han; Marches, Radu; Rossi, Robert J; Nehar-Belaid, Djamel; Eroglu, Alper; Mellert, David J; Kuchel, George A; Banchereau, Jacques; Ucar, Duygu.

Nat Commun; 11(1): 751, 2020 02 06.

Artículo en Inglés | MEDLINE | ID: mdl-32029736

14.

Specific thermal ablation of tumor cells using single-walled carbon nanotubes targeted by covalently-coupled monoclonal antibodies.

Marches, Radu; Chakravarty, Pavitra; Musselman, Inga H; Bajaj, Pooja; Azad, Robert N; Pantano, Paul; Draper, Rockford K; Vitetta, Ellen S.

Int J Cancer; 125(12): 2970-7, 2009 Dec 15.

Artículo en Inglés | MEDLINE | ID: mdl-19536775

15.

The chromatin accessibility signature of human immune aging stems from CD8⁺ T cells.

Ucar, Duygu; Márquez, Eladio J; Chung, Cheng-Han; Marches, Radu; Rossi, Robert J; Uyar, Asli; Wu, Te-Chia; George, Joshy; Stitzel, Michael L; Palucka, A Karolina; Kuchel, George A; Banchereau, Jacques.

J Exp Med; 214(10): 3123-3144, 2017 Oct 02.

Artículo en Inglés | MEDLINE | ID: mdl-28904110

16.

Targeting multiple Her-2 epitopes with monoclonal antibodies results in improved antigrowth activity of a human breast cancer cell line in vitro and in vivo.

Spiridon, Camelia I; Ghetie, Maria-Ana; Uhr, Jonathan; Marches, Radu; Li, Jia-Ling; Shen, Guo-Liang; Vitetta, Ellen S.

Clin Cancer Res; 8(6): 1720-30, 2002 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-12060609

17.

Mathematical models of the fate of lymphoma B cells after antigen receptor ligation with specific antibodies.

Alarcón, Tomás; Marches, Radu; Page, Karen M.

J Theor Biol; 240(1): 54-71, 2006 May 07.

Artículo en Inglés | MEDLINE | ID: mdl-16214175

18.

Cancer dormancy: from mice to man.

Marches, Radu; Scheuermann, Richard; Uhr, Jonathan.

Cell Cycle; 5(16): 1772-8, 2006 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-16929181

19.

Enhancement of the p27Kip1-mediated antiproliferative effect of trastuzumab (Herceptin) on HER2-overexpressing tumor cells.

Marches, Radu; Uhr, Jonathan W.

Int J Cancer; 112(3): 492-501, 2004 Nov 10.

Artículo en Inglés | MEDLINE | ID: mdl-15382077

20.

An anti-CD19 antibody inhibits the interaction between P-glycoprotein (P-gp) and CD19, causes P-gp to translocate out of lipid rafts, and chemosensitizes a multidrug-resistant (MDR) lymphoma cell line.

Ghetie, Maria-Ana; Marches, Radu; Kufert, Stephanie; Vitetta, Ellen S.

Blood; 104(1): 178-83, 2004 Jul 01.

Artículo en Inglés | MEDLINE | ID: mdl-15001473

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Distinct baseline immune characteristics associated with responses to conjugated and unconjugated pneumococcal polysaccharide vaccines in older adults.

Mapping systemic lupus erythematosus heterogeneity at the single-cell level.

Sestrins induce natural killer function in senescent-like CD8⁺ T cells.

Transcriptional activation of Jun and Fos members of the AP-1 complex is a conserved signature of immune aging that contributes to inflammaging.

Concomitant inhibition of PPARÎ³ and mTORC1 induces the differentiation of human monocytes into highly immunogenic dendritic cells.

Distinct baseline immune characteristics associated with responses to conjugated and unconjugated pneumococcal polysaccharide vaccines in older adults.

Young infants display heterogeneous serological responses and extensive but reversible transcriptional changes following initial immunizations.

An unconventional mechanism of IL-1ß secretion that requires Type I IFN in lupus monocytes.

The Th1/Tfh-like biased responses elicited by the rASP-1 innate adjuvant are dependent on TRIF and Type I IFN receptor pathways.

The importance of cellular internalization of antibody-targeted carbon nanotubes in the photothermal ablation of breast cancer cells.

Thermal ablation of tumor cells with antibody-functionalized single-walled carbon nanotubes.

AMULET: a novel read count-based method for effective multiplet detection from single nucleus ATAC-seq data.

Sexual-dimorphism in human immune system aging.

Specific thermal ablation of tumor cells using single-walled carbon nanotubes targeted by covalently-coupled monoclonal antibodies.

The chromatin accessibility signature of human immune aging stems from CD8⁺ T cells.

Targeting multiple Her-2 epitopes with monoclonal antibodies results in improved antigrowth activity of a human breast cancer cell line in vitro and in vivo.

Mathematical models of the fate of lymphoma B cells after antigen receptor ligation with specific antibodies.

Cancer dormancy: from mice to man.

Enhancement of the p27Kip1-mediated antiproliferative effect of trastuzumab (Herceptin) on HER2-overexpressing tumor cells.

An anti-CD19 antibody inhibits the interaction between P-glycoprotein (P-gp) and CD19, causes P-gp to translocate out of lipid rafts, and chemosensitizes a multidrug-resistant (MDR) lymphoma cell line.